The TotiCyte Technology
TotiCyte is a patented reagent formulated from low concentrations of DMSO and Dextran 500. When added to whole blood at a one-to-one ratio, TotiCyte causes the erythrocytes to gently aggregate and rouleaux. This produces a pure, concentrated red cell layer at the bottom of the sample leaving all other blood components, including the white cell fraction, suspended in plasma above. As a result, the plasma, containing all of the buffy coat, platelets and other blood factors, can be extracted and utilised, leaving the waste red cell product behind.